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Merck

COL25A1

collagen, type XXV, alpha 1

Synonymes:
AMY, CLAC, CLAC-P, CLACP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(84570) Summary: This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(77018) collagen, type XXV, alpha 1
  • Rat(687064) collagen, type XXV, alpha 1
  • dog(610442) collagen, type XXV, alpha 1
  • domestic cat(101089352) collagen, type XXV, alpha 1
  • chicken(429900) collagen, type XXV, alpha 1
  • domestic guinea pig(100717264) collagen, type XXV, alpha 1
  • naked mole-rat(101706837) collagen, type XXV, alpha 1
  • Horse(100072894) collagen, type XXV, alpha 1
  • cow(615661) collagen, type XXV, alpha 1
  • sheep(101120576) collagen, type XXV, alpha 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-COL25A1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
dog, human
Application
western blot
Anti-Collagen XXV α1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
Anti-COL25A1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Monoclonal Anti-COL25A1 antibody produced in mouse, clone 1D2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human COL25A1,
Espèce(s)
human