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Merck

CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

Synonymes:
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1140) Summary: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(11443) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • Rat(24261) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic cat(101097433) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Domestic Rabbit(100357163) cholinergic receptor, nicotinic, beta 1 (muscle)
  • sheep(101121614) cholinergic receptor, nicotinic, beta 1 (muscle)
  • naked mole-rat(101723288) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic guinea pig(100714100) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Zebrafish(100006941) cholinergic receptor, nicotinic, beta 1 (muscle)
  • dog(489473) cholinergic receptor, nicotinic, beta 1 (muscle)
  • cow(282179) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Horse(100072990) cholinergic receptor, nicotinic, beta 1 (muscle)

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Decamethonium bromide, Ion-Pair reagent, ≥99%,
Espèce(s)
human
(−)-nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Espèce(s)
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Espèce(s)
human, mouse, rat
Decamethonium bromide, crystalline,
Espèce(s)
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Espèce(s)
human, rat

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Pancuronium bromide, ,
Espèce(s)
human
Cisatracurium besylate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Tubocurarine hydrochloride pentahydrate, ≥97%,
Espèce(s)
human
Atracurium besylate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
(+)-Tubocurarine chloride pentahydrate, ≥97.0% (TLC),
Espèce(s)
human

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Tetraethylammonium chloride, ≥98% (titration),
Espèce(s)
human
Hexamethonium bromide, ,
Espèce(s)
human
Hexamethonium chloride, solid (hygroscopic),
Espèce(s)
human
Acide kynurénique, ≥98%,
Espèce(s)
rat, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CHRNB1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Chrnb1,
Espèce(s)
mouse