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Merck

CHRNA6

cholinergic receptor, nicotinic, alpha 6 (neuronal)

Synonymes:
CHNRA6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8973) Summary: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
  • Mouse(11440) cholinergic receptor, nicotinic, alpha polypeptide 6
  • Rat(81721) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic cat(101098219) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic guinea pig(100723150) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • sheep(101119532) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Horse(100049908) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • chicken(396321) cholinergic receptor, nicotinic, alpha 6
  • Zebrafish(555747) cholinergic receptor, nicotinic, alpha 6
  • dog(482836) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • naked mole-rat(101712413) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • cow(539113) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Domestic Rabbit(100355656) cholinergic receptor, nicotinic, alpha 6 (neuronal)

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Decamethonium bromide, crystalline,
Espèce(s)
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Espèce(s)
human, rat

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Mecamylamine hydrochloride, ,
Espèce(s)
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Espèce(s)
human, rat
Acide kynurénique, ≥98%,
Espèce(s)
rat, human

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Tetraethylammonium chloride, ≥98% (titration),
Espèce(s)
human
Hexamethonium bromide, ,
Espèce(s)
human
Hexamethonium chloride, solid (hygroscopic),
Espèce(s)
human
Acide kynurénique, ≥98%,
Espèce(s)
rat, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CHRNA6,
Espèce(s)
human