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Merck

CDH4

cadherin 4, type 1, R-cadherin (retinal)

Synonymes:
CAD4, RCAD
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1002) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(12561) cadherin 4
  • Rat(114588) cadherin 4
  • naked mole-rat(101726465) cadherin 4, type 1, R-cadherin (retinal)
  • domestic guinea pig(100720758) cadherin 4, type 1, R-cadherin (retinal)
  • sheep(101122716) cadherin 4, type 1, R-cadherin (retinal)
  • chicken(419222) cadherin 4, type 1, R-cadherin (retinal)
  • cow(525796) cadherin 4, type 1, R-cadherin (retinal)
  • dog(100685099) cadherin 4, type 1, R-cadherin (retinal)
  • Zebrafish(30297) cadherin 4, retinal
  • domestic cat(101085708) cadherin 4, type 1, R-cadherin (retinal)

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ELISA

Référence du produit
Description
Espèce(s)
Human Cadherin-4 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CDH4 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, human, mouse, rat
Application
western blot
Anti-CDH4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CDH4,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cdh4,
Espèce(s)
mouse