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Merck

CCND3

cyclin D3

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(896) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  • Mouse(12445) cyclin D3
  • Rat(25193) cyclin D3
  • domestic cat(101101311) cyclin D3
  • Domestic Rabbit(100009038) cyclin D3
  • domestic guinea pig(100718785) cyclin D3
  • naked mole-rat(101708062) cyclin D3
  • sheep(100147798) cyclin D3
  • dog(608847) cyclin D3
  • chicken(419928) cyclin D3
  • cow(540547) cyclin D3
  • Zebrafish(449996) cyclin D3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CCND3 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
western blot
Anti-Cyclin D3 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Cyclin D3 antibody, Rabbit monoclonal, clone SP207, recombinant, expressed in proprietary host, affinity isolated antibody,
Espèces réactives
bovine, human, mouse, rat
Application
flow cytometry
immunohistochemistry

western blot
Anti-CCND3 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-Cyclin D3 (pThr283) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Référence du produit
Description
Espèce(s)
CDK4/CyclinD3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CCND3,
Espèce(s)
human