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Merck

CCL5

chemokine (C-C motif) ligand 5

Synonymes:
D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP
Espèce(s):
Human CCL5 (6352), Mouse Ccl5 (20304), Rat Ccl5 (81780), sheep CCL5 (101115553), domestic guinea pig Ccl5 (100135495), naked mole-rat Ccl5 (101712384), chicken CCL5 (417465), cow CCL5 (327712), Horse CCL5 (100033925), domestic cat CCL5 (493689)
ID UniProtKB:
P13501, O43646, Q0QVW8, Q4ZGJ1, Q9NYA2, Q9UBG2, Q9UC99
ID du gène:
  • Human(6352) Summary: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of two N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
  • Mouse(20304) chemokine (C-C motif) ligand 5
  • Rat(81780) chemokine (C-C motif) ligand 5
  • sheep(101115553) chemokine (C-C motif) ligand 5
  • domestic guinea pig(100135495) chemokine (C-C motif) ligand 5
  • naked mole-rat(101712384) chemokine (C-C motif) ligand 5
  • chicken(417465) chemokine (C-C motif) ligand 5
  • cow(327712) chemokine (C-C motif) ligand 5
  • Horse(100033925) chemokine (C-C motif) ligand 5
  • domestic cat(493689) chemokine (C-C motif) ligand 5
  • dog(403522) chemokine (C-C motif) ligand 5

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ELISA

Référence du produit
Description
Espèce(s)
RAB0076
Human RANTES / CCL5 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
RAB0077
Mouse RANTES / CCL5 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
RAB0527
Feline CCL5 / C-C Motif Chemokine 5 ELISA Kit, for serum, plasma and cell culture supernatants,
Espèce(s)
domestic cat
RAB1827
Rhesus Macaque RANTES ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)

Antibodies

Référence du produit
Description
Espèces réactives
Application
R9400
Monoclonal Anti-RANTES antibody produced in rat, clone 53405.111, purified immunoglobulin, lyophilized powder,
Espèces réactives
mouse
Application
immunocytochemistry
neutralization
R125
Anti-RANTES antibody produced in goat, affinity isolated antibody, lyophilized powder,
Espèces réactives
human
Application
immunohistochemistry
neutralization
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRP3269
RANTES human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Espèce(s)
human
R6267
RANTES human, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU120731
MISSION® esiRNA, targeting human CCL5,
Espèce(s)
human