CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonymes:
CACNA1HB, Cav3.2, ECA6, EIG6
Espèce(s):
Human CACNA1H (8912), Mouse Cacna1h (58226), Rat Cacna1h (114862), dog CACNA1H (403533), domestic cat CACNA1H (101090071), domestic guinea pig Cacna1h (100720102), naked mole-rat Cacna1h (101712631), chicken CACNA1H (416526), cow CACNA1H (282412)
ID UniProtKB:
ID du gène:
- Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
- Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
- Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
- dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
- domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
- domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
- naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
- chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
- cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit
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Small Molecule - Allosteric Modulator
Référence du produit
Description
Espèce(s)
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-Anti-Calcium Channel CaV3.2 (α1H) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
rat
Application
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Blocker
Référence du produit
Description
Espèce(s)
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human