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Merck

ATP6V1B2

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

Synonymes:
ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(526) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
  • Mouse(11966) ATPase, H+ transporting, lysosomal V1 subunit B2
  • Rat(117596) ATPase, H transporting, lysosomal V1 subunit B2
  • cow(338082) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • sheep(494439) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • domestic guinea pig(100726524) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • naked mole-rat(101704199) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • dog(486137) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • domestic cat(101092601) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • Zebrafish(359840) ATPase, H+ transporting, lysosomal V1 subunit B2
  • chicken(395497) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ATP6V1B2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-ATP6V1B2 antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ATP6V1B2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Atp6v1b2,
Espèce(s)
mouse