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Merck

ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

Synonymes:
BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8874) Summary: Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(54126) Rho guanine nucleotide exchange factor (GEF7)
  • Rat(114559) Rho guanine nucleotide exchange factor (GEF) 7
  • domestic cat(101090075) Rho guanine nucleotide exchange factor (GEF) 7
  • chicken(418761) Rho guanine nucleotide exchange factor (GEF) 7
  • dog(485552) Rho guanine nucleotide exchange factor (GEF) 7
  • domestic guinea pig(100717780) Rho guanine nucleotide exchange factor (GEF) 7
  • naked mole-rat(101713994) Rho guanine nucleotide exchange factor (GEF) 7
  • Horse(100066489) Rho guanine nucleotide exchange factor (GEF) 7
  • cow(524352) Rho guanine nucleotide exchange factor (GEF) 7
  • sheep(101116845) Rho guanine nucleotide exchange factor (GEF) 7

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Beta Pix, SH3 Domain Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-ARHGEF7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-ARHGEF7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ARHGEF7,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Arhgef7,
Espèce(s)
mouse