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Merck

ALDOB

aldolase B, fructose-bisphosphate

Synonymes:
ALDB, ALDO2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(229) Summary: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
  • Mouse(230163) aldolase B, fructose-bisphosphate
  • Rat(24190) aldolase B, fructose-bisphosphate
  • sheep(443440) aldolase B, fructose-bisphosphate
  • chicken(427308) aldolase B, fructose-bisphosphate
  • Zebrafish(321664) aldolase b, fructose-bisphosphate
  • dog(474787) aldolase B, fructose-bisphosphate
  • domestic cat(101097025) aldolase B, fructose-bisphosphate
  • Horse(100054480) aldolase B, fructose-bisphosphate
  • domestic guinea pig(100720708) aldolase B, fructose-bisphosphate
  • Domestic Rabbit(100328925) aldolase B, fructose-bisphosphate
  • naked mole-rat(101713582) aldolase B, fructose-bisphosphate
  • cow(515263) aldolase B, fructose-bisphosphate

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ALDOB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Anti-Aldob Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-ALDOB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Kits

Référence du produit
Description
Espèce(s)
Aldolase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Espèce(s)
mouse, human, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ALDOB,
Espèce(s)
human