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Merck

ACACA

acetyl-CoA carboxylase alpha

Synonymes:
ACAC, ACACAD, ACC, ACC1, ACCA
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(31) Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(107476) acetyl-Coenzyme A carboxylase alpha
  • Rat(60581) acetyl-CoA carboxylase alpha
  • dog(491130) acetyl-CoA carboxylase alpha
  • chicken(396504) acetyl-CoA carboxylase alpha
  • Zebrafish(559403) acetyl-Coenzyme A carboxylase alpha
  • cow(281590) acetyl-CoA carboxylase alpha
  • Horse(100071472) acetyl-CoA carboxylase alpha
  • domestic cat(101083046) acetyl-CoA carboxylase alpha
  • Domestic Rabbit(100355970) acetyl-CoA carboxylase alpha
  • Goat(100861224) acetyl-CoA carboxylase alpha
  • sheep(443186) acetyl-CoA carboxylase alpha
  • naked mole-rat(101706028) acetyl-CoA carboxylase alpha
  • domestic guinea pig(100733410) acetyl-CoA carboxylase alpha

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-phospho-Acetyl CoA Carboxylase (Ser79) Antibody, Upstate®, from rabbit,
Espèces réactives
bovine, canine, chicken, dog, human, mouse, rat
Application
western blot
Anti-ACC1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Acetyl-CoA Carboxylase, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Acetyl CoA Carboxylase 1, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-phospho-Acetyl CoA Carboxylase (Ser79) Antibody, clone BK102, clone BK102, Upstate®, from mouse,
Espèces réactives
mouse, rat
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
Acetyl-CoA Carboxylase 1 human, recombinant, expressed in Sf9 cells,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ACACA (1),
Espèce(s)
human
MISSION® esiRNA, targeting mouse Acaca,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ACACA (2),
Espèce(s)
human