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  • Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.

Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.

Food additives & contaminants. Part B, Surveillance (2014-12-30)
JeongWoo Kang, Hae-Chul Park, Vinayakumar Gedi, Su-Jeong Park, Myeong-Ae Kim, Min-Kyoung Kim, Hyun-Jung Kwon, Byung-Hoon Cho, Tae-Wan Kim, Kwang-Jick Lee, Chae-Mi Lim
ABSTRACT

The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test programme. Monitoring and surveillance/enforcement testing programmes are routinely implemented by 17 Provincial Veterinary Services for domestic products and regional offices of the Animal and Plant Quarantine Agency (QIA) for imported products. The exploratory project conducted at QIA headquarters is designed to test substances that are not included in monitoring and enforcement testing programmes. Here, we carried out exploratory testing for determining the presence of 42 veterinary drugs that have no established Korean maximum residue limits and analysed their levels simultaneously, in a total of 3108 samples of domestic and imported animal-origin foods. Of the tested drugs, acetylsalicylic, paracetamol, clopidol, diclazuril, amprolium, toltrazuril and its metabolites (toltrazuril sulphone and toltrazuril sulphoxide) and phenylbutazone and its metabolites (oxyphenylbutazone) were detected.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Acetic acid, natural, ≥99.5%, FG
Sigma-Aldrich
Acetic acid, ≥99.5%, FCC, FG
Sigma-Aldrich
Ethylene, ≥99.5%
Sigma-Aldrich
Acetylsalicylic acid, analytical standard
Sigma-Aldrich
Amprolium hydrochloride
Sigma-Aldrich
Acetylsalicylic acid, ≥99.0%
Sigma-Aldrich
Prednisolone, ≥99%
Sigma-Aldrich
Prednisone, ≥98%
Sigma-Aldrich
Phenylbutazone
Sigma-Aldrich
Acetic acid, for luminescence, BioUltra, ≥99.5% (GC)
Sigma-Aldrich
Acetic acid-12C2, 99.9 atom % 12C
Sigma-Aldrich
5α-Androstan-17β-ol-3-one, purum, ≥99.0% (TLC)
Sigma-Aldrich
Acetonitrile, anhydrous, 99.8%
Sigma-Aldrich
Aspirin, meets USP testing specifications
Sigma-Aldrich
Dexamethasone, powder, BioReagent, suitable for cell culture, ≥97%
Sigma-Aldrich
Dexamethasone, meets USP testing specifications
Sigma-Aldrich
Dexamethasone, ≥98% (HPLC), powder
Sigma-Aldrich
Tolfenamic acid, NSAID
Sigma-Aldrich
Betamethasone, ≥98%
Sigma-Aldrich
Flumethasone
Sigma-Aldrich
Dexamethasone, powder, γ-irradiated, BioXtra, suitable for cell culture, ≥80% (HPLC)
Sigma-Aldrich
Nicarbazin
Sigma-Aldrich
Acetonitrile, electronic grade, 99.999% trace metals basis
Sigma-Aldrich
Ultrapure Acetonitrile