- Green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives in ionic liquids.
Green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives in ionic liquids.
Journal of combinatorial chemistry (2009-09-22)
Xiang-Shan Wang, Jian-Rong Wu, Jie Zhou, Shu-Jiang Tu
PMID19764713
ABSTRACT
An efficient and green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives has been developed. The synthesis was achieved by using a multicomponent procedure in ionic liquid media. The features of this procedure are characterized by the following: mild reaction conditions, high yields, one-pot procedures, operational simplicity, and environmentally benign conditions.