Ceric ammonium nitrate promoted oxidation of oxazoles.

Ceric ammonium nitrate promoted oxidation of oxazoles.

Organic letters (2006-11-17)

David A Evans, Pavel Nagorny, Risheng Xu

ABSTRACT

The ceric ammonium nitrate promoted oxidations of 4,5-diphenyloxazoles and oxazoles with various substitution patterns have been investigated. This transformation results in the formation of the corresponding imide in good yield and tolerates a wide variety of functional groups and substituents on the oxazole moiety. [reaction: see text].

MATERIALS

Product Number

Brand

Product Description

229547

Sigma-Aldrich

Ammonium cerium(IV) nitrate, ≥99.99% trace metals basis

C3654

Sigma-Aldrich

Ammonium cerium(IV) nitrate, ≥98% (titration)

215473

Sigma-Aldrich

Ammonium cerium(IV) nitrate, ACS reagent, ≥98.5%

22249

Sigma-Aldrich

Ammonium cerium(IV) nitrate, puriss. p.a., ACS reagent, ≥98.5% (RT)