This product can be dissolved in ethanol and solutions can be stored in frozen aliquots avoiding repetitive freeze/thaws cycles.
E8875
17β-Estradiol
≥98% (HPLC), powder, estrogenic hormone
Synonym(s):
1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin
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About This Item
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Product Name
β-Estradiol, ≥98%
biological source
synthetic (organic)
sterility
non-sterile
Assay
≥98%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
176-180 °C (lit.)
solubility
ethanol: 50 mg/mL, clear, colorless
shipped in
ambient
storage temp.
room temp
SMILES string
O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
Gene Information
human ... ESR1(2099) , ESR2(2100) , ESRRA(2101) , ESRRB(2103) , GPER(2852) , SERPINA6(866)
mouse ... Esr1(13982) , Esr2(13983) , Esrra(26379)
rat ... Afp(24177) , Ar(24208) , Esr1(24890) , Esr2(25149) , Shbg(24775)
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General description
Application
Biochem/physiol Actions
Features and Benefits
related product
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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Customers Also Viewed
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Can I dissolve E8875-1G with ethanol and keep it below -20℃?
1 answer-
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Which of the two options, E1024 or E8875, is preferable for use as 1) an oral supplement and 2) silastic tube release? Additionally, among these which one is better for dissolving estrogen in sesame oil.
1 answer-
The in vivo application is beyond the scope of product characterization efforts. However, for the specified applications, E8875 is highly recommended, as it has been well cited in the literature. The following publications may be of interest for protocol reference:
1. J Vis Exp. 2012 Jun 7;(64):e4013. Ovariectomy and 17β-estradiol replacement in rats and mice: a visual demonstration. PMID: 22710371
2. Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R587-92. Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome. PMID: 19439618
3. Eur J Pharmacol. 2021 May 25;906:174175. Apigenin acts as a partial agonist action at estrogen receptors in vivo. PMID: 34048736
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