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Merck

TNFRSF4

tumor necrosis factor receptor superfamily, member 4

Synonyms:
ACT35, CD134, OX40, TXGP1L
Species:
UniProtKB ID:
Gene ID:
  • Human(7293) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
  • Mouse(22163) tumor necrosis factor receptor superfamily, member 4
  • Rat(25572) tumor necrosis factor receptor superfamily, member 4
  • domestic guinea pig(100715179) tumor necrosis factor receptor superfamily, member 4
  • cow(528782) tumor necrosis factor receptor superfamily, member 4
  • Domestic Rabbit(100009449) tumor necrosis factor receptor superfamily, member 4
  • chicken(101751037) tumor necrosis factor receptor superfamily, member 4
  • sheep(101108407) tumor necrosis factor receptor superfamily, member 4
  • naked mole-rat(101714706) tumor necrosis factor receptor superfamily, member 4
  • domestic cat(493665) tumor necrosis factor receptor superfamily, member 4
  • chicken(101665445) tumor necrosis factor receptor superfamily, member 4
  • dog(489600) tumor necrosis factor receptor superfamily, member 4

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ELISA

Product Number
Description
Species
Human OX40 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD134 antibody produced in mouse, clone Ber-ACT35,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
Anti-TNR4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
Anti-OX40 (CD134) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM313, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-CD134-APC antibody produced in mouse, clone Ber-ACT35,
Species Reactivity
Application
flow cytometry

Proteins

Product Number
Description
Species
OX40 (CD134), Biotin Labeled, His-Tag, recombinant, expressed in HEK 293 cells,
Species
human