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Merck

LDOC1

leucine zipper, down-regulated in cancer 1

Synonyms:
BCUR1, Mar7, Mart7
Species:
UniProtKB ID:
Gene ID:
  • Human(23641) Summary: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]
  • Mouse(434784) leucine zipper, down-regulated in cancer 1
  • Rat(367956) leucine zipper, down-regulated in cancer 1
  • dog(492180) leucine zipper, down-regulated in cancer 1
  • cow(616591) leucine zipper, down-regulated in cancer 1

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LDOC1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-LDOC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ldoc1,
Species
mouse
MISSION® esiRNA, targeting human LDOC1,
Species
human