ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms:
ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Species:
Human ENPP2 (5168), Mouse Enpp2 (18606), Rat Enpp2 (84050), dog ENPP2 (482026), chicken ENPP2 (420361), Zebrafish enpp2 (393575), naked mole-rat Enpp2 (101710936), domestic guinea pig Enpp2 (100722506), cow ENPP2 (532663), sheep ENPP2 (101120171) ...More
UniProtKB ID:
Gene ID:
- Human(5168) Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
- Mouse(18606) ectonucleotide pyrophosphatase/phosphodiesterase 2
- Rat(84050) ectonucleotide pyrophosphatase/phosphodiesterase 2
- dog(482026) ectonucleotide pyrophosphatase/phosphodiesterase 2
- chicken(420361) ectonucleotide pyrophosphatase/phosphodiesterase 2
- Zebrafish(393575) ectonucleotide pyrophosphatase/phosphodiesterase 2
- naked mole-rat(101710936) ectonucleotide pyrophosphatase/phosphodiesterase 2
- domestic guinea pig(100722506) ectonucleotide pyrophosphatase/phosphodiesterase 2
- cow(532663) ectonucleotide pyrophosphatase/phosphodiesterase 2
- sheep(101120171) ectonucleotide pyrophosphatase/phosphodiesterase 2
- domestic cat(101097620) ectonucleotide pyrophosphatase/phosphodiesterase 2
- Horse(100057101) ectonucleotide pyrophosphatase/phosphodiesterase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ENPP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
western blot
Anti-ENPP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ENPP2 antibody produced in mouse, purified immunoglobulin,
Species Reactivity
human
Application
western blot
Anti-Autotaxin Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Autotaxin (ENPP2) Antibody, clone 7A5, clone 7A5, from mouse,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
ENPP2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human