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Merck

DCTN3

dynactin 3 (p22)

Synonyms:
DCTN-22, DCTN22
Species:
UniProtKB ID:
Gene ID:
  • Human(11258) Summary: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(53598) dynactin 3
  • Rat(362504) dynactin 3
  • sheep(101121236) dynactin 3 (p22)
  • domestic guinea pig(100726120) dynactin 3 (p22)
  • naked mole-rat(101706314) dynactin 3 (p22)
  • Zebrafish(431767) dynactin 3 (p22)
  • chicken(427404) dynactin 3 (p22)
  • dog(474750) dynactin 3 (p22)
  • domestic cat(101083978) dynactin 3 (p22)
  • cow(514327) dynactin 3 (p22)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DCTN3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-DCTN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-DCTN3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
flow cytometry

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DCTN3,
Species
human
MISSION® esiRNA, targeting mouse Dctn3,
Species
mouse