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Merck

CHRNA6

cholinergic receptor, nicotinic, alpha 6 (neuronal)

Synonyms:
CHNRA6
Species:
UniProtKB ID:
Gene ID:
  • Human(8973) Summary: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
  • Mouse(11440) cholinergic receptor, nicotinic, alpha polypeptide 6
  • Rat(81721) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic cat(101098219) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic guinea pig(100723150) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • sheep(101119532) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Horse(100049908) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • chicken(396321) cholinergic receptor, nicotinic, alpha 6
  • Zebrafish(555747) cholinergic receptor, nicotinic, alpha 6
  • dog(482836) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • naked mole-rat(101712413) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • cow(539113) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Domestic Rabbit(100355656) cholinergic receptor, nicotinic, alpha 6 (neuronal)

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Small Molecule - Agonist

Product Number
Description
Species
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Mecamylamine hydrochloride, ,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat
Kynurenic acid, ≥98%,
Species
rat, human

Small Molecule - Blocker

Product Number
Description
Species
Hexamethonium bromide, ,
Species
human
Hexamethonium chloride, solid (hygroscopic),
Species
human
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHRNA6,
Species
human