ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
Synonyms:
ABC42, ALD, ALDP, AMN
Species:
Human ABCD1 (215), Mouse Abcd1 (11666), Rat Abcd1 (363516), sheep ABCD1 (101122673), Domestic Rabbit ABCD1 (100328741), Zebrafish abcd1 (566367), dog ABCD1 (612520), domestic cat ABCD1 (101088223), cow ABCD1 (515178), naked mole-rat Abcd1 (101720585)
UniProtKB ID:
Gene ID:
- Human(215) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
- Mouse(11666) ATP-binding cassette, sub-family D (ALD), member 1
- Rat(363516) ATP-binding cassette, subfamily D (ALD), member 1
- sheep(101122673) ATP-binding cassette, sub-family D (ALD), member 1
- Domestic Rabbit(100328741) ATP-binding cassette, sub-family D (ALD), member 1
- Zebrafish(566367) ATP-binding cassette, sub-family D (ALD), member 1
- dog(612520) ATP-binding cassette, sub-family D (ALD), member 1
- domestic cat(101088223) ATP-binding cassette, sub-family D (ALD), member 1
- cow(515178) ATP-binding cassette, sub-family D (ALD), member 1
- naked mole-rat(101720585) ATP-binding cassette, sub-family D (ALD), member 1
- domestic guinea pig(100713152) ATP-binding cassette, sub-family D (ALD), member 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ABCD1, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
Monoclonal Anti-ABCD1 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-Adrenoleukodystrophy Protein Antibody, a.a. 279-482, clone 2AL-1D6, ascites fluid, clone 2AL-1D6, Chemicon®,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot