Aryl-heteroaryl derivatives as novel wake-promoting agents.

Aryl-heteroaryl derivatives as novel wake-promoting agents.

Chemical biology & drug design (2012-11-01)

Brigitte Lesur, Yin G Lin, Val R Marcy, Lisa D Aimone, John Gruner, Edward R Bacon, Sankar Chatterjee

ZUSAMMENFASSUNG

In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually.

MATERIALIEN

Produktnummer

Marke

Produktbeschreibung

M-084

Supelco

Modafinil -Lösung, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

Y0000635

Modafinil, European Pharmacopoeia (EP) Reference Standard

Y0000636

Modafinil für die Systemeignung, European Pharmacopoeia (EP) Reference Standard