SRP6318

Kininogen,HMW from human plasma

≥95% (SDS-PAGE)

• Synonym(e): Alpha-2-thiol proteinase inhibitor, BDK, Fitzgerald factor, High molecular weight Kininogen, KNG, Kininogen-1 heavy chain, Kininogen-1 light chain, Low molecular weight growth-promoting, Lysyl-bradykinin, T-kinin Bradykinin, Williams-Fitzgerald-Flaujeac factor
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human plasma
• Assay: ≥95% (SDS-PAGE)
• Form: frozen liquid
• Mol-Gew.: 120 kDa
• Verpackung: pkg of 100 μg
• UniProt-Hinterlegungsnummer: P01042
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... KNG1(3827)

Beschreibung

Allgemeine Beschreibung

HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.

Physikalische Form

Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H319,H334,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable