SAB4300647

Anti-GFAP antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-FLJ45472
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~50 kDa
• Speziesreaktivität: rat, human
• Konzentration: 1 mg/mL
• Methode(n): western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (E-S-K-Q-E)
• NCBI-Hinterlegungsnummer: NM_002055.3
• UniProt-Hinterlegungsnummer: P14136
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... GFAP(2670)

Beschreibung

Allgemeine Beschreibung

Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system).{56,59} It is located on chromosome 17q21.

The antibody detects endogenous level of total GFAP protein.

Immunogen

Peptide sequence around aa. 423-427 (E-S-K-Q-E), according to the protein NP_002046.1

Biochem./physiol. Wirkung

Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions. It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable