B108

Benzatropin -methansulfonat (Salz)

• Synonym(e): Benzatropine mesylate, Benzotropine mesylate, Benztropine methanesulfonate
• Empirische Formel (Hill-System): C₂₁H₂₅NO · CH₃SO₃H
• CAS-Nummer: 132-17-2
• Molekulargewicht: 403.53
• EG-Nummer: 205-048-8
• MDL-Nummer: MFCD00074784
• UNSPSC-Code: 12352200

Eigenschaften

• SMILES String: CS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c3ccccc3)c4ccccc4
• InChI: 1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;
• InChIKey: CPFJLLXFNPCTDW-BWSPSPBFSA-N

Beschreibung

Biochem./physiol. Wirkung

Benztropine mesylate is a centrally acting muscarinic acetylcholine receptor antagonist and dopamine transporter (DAT) inhibitor (IC₅₀ = 118 nM). Benztropine mesylate has been used to treat the symptoms of Parkinson′s disease and is currently in clincial trials for chronic back pain.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H302,H311 + H331
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges