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A5284

Sigma-Aldrich

8-Azaguanin

Hybri-Max™, γ-irradiated, powder, BioXtra, suitable for hybridoma

Synonym(e):

2-Amino-6-hydroxy-8-azapurin, Guanazolo

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About This Item

Empirische Formel (Hill-System):
C4H4N6O
CAS-Nummer:
134-58-7
Molekulargewicht:
152.11
Beilstein:
171098
EG-Nummer:
205-148-1
MDL-Nummer:
MFCD00056937
UNSPSC-Code:
12352207
PubChem Substanz-ID:
24890963

Qualität

Hybri-Max™

Sterilität

γ-irradiated

Produktlinie

BioXtra

Form

powder

Methode(n)

cell culture | hybridoma: suitable

mp (Schmelzpunkt)

>300 °C (lit.)

Lagertemp.

−20°C

SMILES String

NC1=Nc2[nH]nnc2C(=O)N1

InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

InChIKey

LPXQRXLUHJKZIE-UHFFFAOYSA-N

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Anwendung

For use in hybridoma cell culture applications as a myeloma selection agent.

Rekonstituierung

Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium.

Rechtliche Hinweise

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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July Fong et al.
Scientific reports, 8(1), 1155-1155 (2018-01-20)
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeting
Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
Ziwei Li et al.
International journal of oncology, 52(6), 2079-2092 (2018-04-06)
Hepatocellular carcinoma (HCC) is one of the most common malignancies and causes of death worldwide. Research investigating novel therapeutic strategies for the treatment of HCC is urgently required. Monoclonal antibodies (mAbs) that target the programmed cell death‑1 (PD‑1/PDCD1)/programmed death-ligand 1
M Schiltz et al.
Carcinogenesis, 20(12), 2279-2286 (1999-12-11)
Earlier studies have shown that the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (+)-BPDE at the hypoxanthine (guanine) phosphoribosyltransferase (hprt) gene of Chinese hamster V79 cells was dependent on the concentration of (+)-BPDE. In the present study, we examined the effect
T L Bowen et al.
Journal of bacteriology, 178(9), 2521-2526 (1996-05-01)
Phosphoribosyltransferase (PRTase) and nucleoside phosphorylase (NPase) activities were detected by radiometric methods in extracts of Methanococcus voltae. Guanine PRTase activity was present at 2.7 nmol min(-1) mg of protein(-1) and had an apparent Km for guanine of 0.2 mM and
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