1.08178

Trifluoressigsäure

for protein sequence analysis

• Synonym(e): TFA
• Lineare Formel: CF₃COOH
• CAS-Nummer: 76-05-1
• Molekulargewicht: 114.02
• Beilstein: 742035
• MDL-Nummer: MFCD00004169
• UNSPSC-Code: 12352106
• EG-Index-Nummer: 200-929-3
• NACRES: NA.21

Eigenschaften

• Dampfdichte: 3.9 (vs air)
• Qualitätsniveau: 200
• Dampfdruck: 97.5 mmHg ( 20 °C)
• Assay: ≥99.7% (acidimetric)
• Form: liquid
• Verunreinigungen: ≤0.02% Water (Karl Fischer)
• Brechungsindex: n20/D 1.3 (lit.)
• pH-Wert: 1 (10 g/L in H₂O)
• bp: 72.4 °C (lit.)
• mp (Schmelzpunkt): −15.4 °C (lit.)
• Löslichkeit: soluble 10 g/mL
• Dichte: 1.489 g/mL at 20 °C (lit.)
• Lagertemp.: 2-30°C
• SMILES String: OC(C(F)(F)F)=O
• InChI: 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChIKey: DTQVDTLACAAQTR-UHFFFAOYSA-N

Beschreibung

Anwendung

Trifluoroacetic acid (TFA) can be used as an ion-pairing agent in a reverse-phase HPLC system to separate peptides because it enhances peak resolution. It also has low absorption detection wavelengths and is relatively volatile and can be easily removed. For the majority of peptide separations, TFA has been used at concentrations ranging from 0.05 to 0.1%(6.5-13 mM).

Hinweis zur Analyse

Gehalt (acidimetrisch): ≥ 99.7 %
Identität (IR-Spektrum): entspricht
Dichte (d 20 °C/20 °C): ca. 1.53
Siedepunkt: ca. 72 °C
Wasser (nach Karl Fischer): ≤ 0.02 %

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H314 - H332 - H412
• P-Sätze: P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• Lagerklassenschlüssel: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 2
• Flammpunkt (°F): 212.0 °F - Pensky-Martens closed cup
• Flammpunkt (°C): > 100 °C - Pensky-Martens closed cup