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Merck

790427C

Avanti

06:0 PC-d22

Avanti Research - A Croda Brand 790427C

Synonym(e):

1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine

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About This Item

Empirische Formel (Hill-System):
C20H18NO8PD22
CAS-Nummer:
Molekulargewicht:
475.64
UNSPSC-Code:
12352211
NACRES:
NA.12

Assay

>99% (TLC)

Form

liquid

Verpackung

pkg of 1 × 1 mL (790427C-10mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 790427C

Konzentration

10 mg/mL (790427C-10mg)

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Phosphatidylcholine is a zwitterionic glycerophospholipid, containing choline. It consists of a head and two tails. Head group contains choline and phosphate. Head is polar and water soluble. The tail group contains two fatty acyl chains esterified with glycerol. Tail group is non-polar and water-insoluble. Phosphatidylcholine is synthesized in the liver by phosphatidylethanolamine methyltransferase (PEMT) pathway. It is also synthesized by the Kennedy pathway and the Lands cycle.

Anwendung

06:0 PC-d22 (1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine) has been used:
  • as bicelles for lipid in HN-HN nuclear overhauser enhancement (NOE) detection
  • as an internal standard in residual algal suspension for liquid chromatography-mass spectrometry analysis (LC-MS/MS)
  • to produce bicelles to investigate C-peptide and membrane interaction by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)

Biochem./physiol. Wirkung

Phosphatidylcholine (PC) is a major component of the membrane bilayer. It is involved in the synthesis of signaling molecules. PC is the precursor for the synthesis of sphingomyelin and phosphatidylserine.

Verpackung

5 mL Clear Glass Sealed Ampule (790427C-10mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system

WGK

WGK 3


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

pH-dependent interaction between C-peptide and phospholipid bicelles
Unnerstaale S and Maler L
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012(1), 43-43 (2012)
Biochemistry of Lipids, Lipoproteins and Membranes (2015)
Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
Moessinger C, et al.
BMC Cell Biology, 15(1), 43-43 (2014)
Metabolic and morphological changes of an oil accumulating trebouxiophycean alga in nitrogen-deficient conditions
Ito T, et al.
Metabolomics, 9(1), 178-187 (2013)
The unusual transmembrane partition of the hexameric channel of the hepatitis C virus
Chen W, et al.
Structure, 26(4), 627-634 (2018)

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