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SET

SET nuclear oncogene

Synonyme:
2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6418) Summary: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(56086) SET nuclear oncogene
  • Rat(307947) SET nuclear oncogene
  • fruit fly(41844) CG4299 gene product from transcript CG4299-RA
  • chicken(417210) SET nuclear oncogene
  • dog(608952) SET nuclear oncogene
  • domestic cat(101081583) SET nuclear oncogene
  • cow(538444) SET nuclear oncogene
  • sheep(101118680) SET nuclear oncogene
  • domestic guinea pig(100715138) SET nuclear oncogene
  • naked mole-rat(101720656) SET nuclear oncogene

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-SET antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-SET, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-SET-beta, clone 3D10E2, clone 3D10E2, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-SET-alpha, clone 5F4D9, clone 5F4D9, from mouse,
Speziesreaktivität
human
Anwendung
western blot
Monoclonal Anti-SET antibody produced in mouse, clone M1-F5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Set,
Spezies
mouse