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KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1

Synonyme:
KIR1.1, ROMK, ROMK1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3758) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56379) potassium inwardly-rectifying channel, subfamily J, member 1
  • Rat(24521) potassium inwardly-rectifying channel, subfamily J, member 1
  • chicken(428236) potassium inwardly-rectifying channel, subfamily J, member 1
  • Horse(100072580) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic cat(101091140) potassium inwardly-rectifying channel, subfamily J, member 1
  • cow(539250) potassium inwardly-rectifying channel, subfamily J, member 1
  • dog(489285) potassium inwardly-rectifying channel, subfamily J, member 1
  • naked mole-rat(101720253) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic guinea pig(100722828) potassium inwardly-rectifying channel, subfamily J, member 1

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Small Molecule - Activator

Produktnummer
Beschreibung
Spezies
Diazoxid, ,
Spezies
rat, mouse, human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Cromakalim, ,
Spezies
rat
Glyburid, meets USP testing specifications,
Spezies
rat, human
Glybenclamid, ≥99% (HPLC),
Spezies
rat, human
Chlorpropamid, analytical standard, ≥97%,
Spezies
human, mouse
Tolbutamid, analytical standard,
Spezies
human, mouse

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-KCNJ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-KCNJ1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, guinea pig, horse, human, rabbit, rat
Anwendung
western blot
Anti-ROMK antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
Anti-KCNJ1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Gliclazid, powder, ≥98%,
Spezies
human
Glimepirid, ≥98% (HPLC), solid,
Spezies
human
Repaglinid, ≥98% (HPLC), solid,
Spezies
human
Glipizid, solid,
Spezies
human
Glyburid, meets USP testing specifications,
Spezies
rat, human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Linopirdin, ≥98% (HPLC),
Spezies
rat
VU591, ≥98% (HPLC),
Spezies
human
Tertiapin-Q trifluoroacetate salt, ≥97% (HPLC),
Spezies
rat, human, mouse
Chlorpropamid, analytical standard, ≥97%,
Spezies
human, mouse
Tolbutamid, analytical standard,
Spezies
human, mouse

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Glimepirid, ≥98% (HPLC), solid,
Spezies
human
Glipizid, solid,
Spezies
human
Glybenclamid, ≥99% (HPLC),
Spezies
rat, human
Chlorpropamid, analytical standard, ≥97%,
Spezies
human, mouse

Small Molecule - Opener

Produktnummer
Beschreibung
Spezies
Minoxidil, ≥99% (TLC),
Spezies
human
Diazoxid, ,
Spezies
rat, mouse, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human KCNJ1,
Spezies
human