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Merck

KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

Synonyme:
ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3757) Summary: This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(16511) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Rat(117018) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Zebrafish(405763) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • naked mole-rat(101711977) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • domestic cat(101081621) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Horse(100064000) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Domestic Rabbit(100009242) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • dog(403761) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • domestic guinea pig(100135563) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • cow(539971) potassium voltage-gated channel, subfamily H (eag-related), member 2

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Sotalol -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Sotalol -hydrochlorid, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
(±)-Sotalol -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
Glyburid, meets USP testing specifications,
Spezies
rat, human
Glybenclamid, ≥99% (HPLC),
Spezies
rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Potassium Channel KV11.1 (HERG) Extracellular-FITC in Kaninchen hergestellte Antikörper, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry
Anti-KCNH2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot
Anti-Potassium Channel HERG Antibody, CT, Chemicon®, from rabbit,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Kaliumkanal-ERG1-Antikörper, C-Terminus, Chemicon®, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv11.1 Extracellular antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry

western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Dofetilid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Amiodaron -hydrochlorid -Lösung, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Ibutilid -hemifumarat (Salz), ≥98% (HPLC),
Spezies
human
Ibutilidfumarat, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 885.23 ([(C20H36N2O3S)2 . C4H4O4]),
Spezies
human
Sotalol -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Loratadin, ≥98% (HPLC), powder,
Spezies
rat, human
Terfenadin, ,
Spezies
mouse, rat, human
Pimozid, ,
Spezies
human, mouse, rat
Haloperidol, powder,
Spezies
human, rat
Clozapin, ,
Spezies
human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human KCNH2,
Spezies
human