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Merck

HRAS

Harvey rat sarcoma viral oncogene homolog

Synonyme:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(293621) Harvey rat sarcoma virus oncogene
  • dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Guanosin 5′-triphosphat Natriumsalz Hydrat, ≥95% (HPLC), powder,
Spezies
human
Inosin-5′-Triphosphat Trinatriumsalz, ≥95%,
Spezies
human
Guanosin-5′-triphosphat Natriumsalz -Lösung, HPLC purified, aqueous solution for RNA polymerase transcription,
Spezies
human
2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt, ≥90% (HPLC),
Spezies
human
Erastin, ≥98% (HPLC),
Spezies
mouse, rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
Speziesreaktivität
human
Anwendung
western blot
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
Speziesreaktivität
human, mouse, rat
Anwendung
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
affinity binding assay

western blot
Anti-Ha-Ras Antibody, clone MC57, rabbit monoclonal, culture supernatant, clone MC57, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-HRAS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human HRAS,
Spezies
human