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Merck

GZMB

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Synonyme:
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3002) Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
  • Mouse(14939) granzyme B
  • Rat(171528) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic guinea pig(100736180) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • dog(490630) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(508646) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(281731) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • Horse(100033978) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic cat(100127106) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • naked mole-rat(101702156) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

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ELISA

Produktnummer
Beschreibung
Spezies
Mouse Granzyme B ELISA Kit, for serum, plasma and cell culture supernatant,
Spezies
mouse
Human Granzyme B ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Granzyme B Antibody, clone GrB-7, culture supernatant, clone GrB-7, Chemicon®,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-Granzyme B Antibody, clone 3M4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
ELISA
affinity binding assay

flow cytometry

western blot
Anti-GZMB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Monoclonal Anti-GZMB antibody produced in mouse, clone CLB-GB11, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, nonhuman primates
Anwendung
flow cytometry
Anti-Granzyme B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
Granzyme B human, recombinant, expressed in insect cells, ≥90% (SDS-PAGE),
Spezies
human
Granzyme B from mouse, recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Spezies
mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GZMB,
Spezies
human

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,
Spezies
rat, mouse, human
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide, ≥95%,
Spezies
rat, mouse, human
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Spezies
rat, mouse, human
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Spezies
rat, mouse, human