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GRPR

gastrin-releasing peptide receptor

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2925) Summary: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
  • Mouse(14829) gastrin releasing peptide receptor
  • Rat(24938) gastrin releasing peptide receptor
  • Zebrafish(567289) gastrin-releasing peptide receptor
  • naked mole-rat(101701702) gastrin-releasing peptide receptor
  • cow(532784) gastrin-releasing peptide receptor
  • chicken(378928) gastrin-releasing peptide receptor
  • domestic cat(101096951) gastrin-releasing peptide receptor
  • dog(491754) gastrin-releasing peptide receptor
  • domestic guinea pig(100734491) gastrin-releasing peptide receptor
  • Horse(100056400) gastrin-releasing peptide receptor
  • sheep(100142675) gastrin-releasing peptide receptor
  • Domestic Rabbit(100344857) gastrin-releasing peptide receptor

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Bombesin, ≥97% (HPLC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ANTI-GRPR (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
flow cytometry
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Grpr,
Spezies
mouse
MISSION® esiRNA, targeting human GRPR,
Spezies
human