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GCSH

glycine cleavage system protein H (aminomethyl carrier)

Synonyme:
GCE, NKH
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2653) Summary: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]
  • Mouse(68133) glycine cleavage system protein H (aminomethyl carrier)
  • Rat(171133) glycine cleavage system protein H (aminomethyl carrier)
  • cow(317723) glycine cleavage system protein H (aminomethyl carrier)
  • sheep(101120772) glycine cleavage system protein H (aminomethyl carrier)
  • Domestic Rabbit(100009476) glycine cleavage system protein H (aminomethyl carrier)
  • dog(479633) glycine cleavage system H protein, mitochondrial-like
  • chicken(415803) glycine cleavage system protein H (aminomethyl carrier)
  • domestic cat(101084333) glycine cleavage system protein H (aminomethyl carrier)
  • domestic guinea pig(100721850) glycine cleavage system protein H (aminomethyl carrier)
  • naked mole-rat(101724619) glycine cleavage system protein H (aminomethyl carrier)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GCSH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-GCSH antibody produced in mouse, clone 3D8-A12, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-GCSH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GCSH,
Spezies
human
MISSION® esiRNA, targeting mouse Gcsh,
Spezies
mouse