Direkt zum Inhalt
Merck

F3

coagulation factor III (thromboplastin, tissue factor)

Synonyme:
CD142, TF, TFA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2152) Summary: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(14066) coagulation factor III
  • Rat(25584) coagulation factor III (thromboplastin, tissue factor)
  • naked mole-rat(101702267) coagulation factor III (thromboplastin, tissue factor)
  • domestic guinea pig(100135463) coagulation factor III
  • Domestic Rabbit(100009127) coagulation factor III (thromboplastin, tissue factor)
  • sheep(101118918) coagulation factor III (thromboplastin, tissue factor)
  • cow(280686) coagulation factor III
  • domestic cat(101082330) coagulation factor III (thromboplastin, tissue factor)
  • dog(490153) coagulation factor III (thromboplastin, tissue factor)
  • chicken(429084) coagulation factor III (thromboplastin, tissue factor)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Produktnummer
Beschreibung
Spezies
Human F3 / Tissue Factor ELISA Kit, ,
Spezies
human
MouseCoagulation Factor III ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Spezies
mouse

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-CD142 PE produced in mouse, ,
Speziesreaktivität
human
Anwendung
flow cytometry
Anti-Tissue Factor Antibody, clone 2L10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Tissue Factor/CD142 Antibody, clone HTF-1, ,
Speziesreaktivität
bovine, human
Anwendung
ELISA
dot blot

flow cytometry

immunohistochemistry

inhibition assay

western blot
Monoclonal Anti-CD142 antibody produced in mouse, clone HTF-1,
Speziesreaktivität
human
Anwendung
flow cytometry
Anti-F3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence

Proteins

Produktnummer
Beschreibung
Spezies
Thromboplastin aus Kaninchen, ,
Spezies
domestic rabbit

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human F3,
Spezies
human