Direkt zum Inhalt
Merck

ATP1B1

ATPase, Na+/K+ transporting, beta 1 polypeptide

Synonyme:
ATP1B
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(481) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
  • Mouse(11931) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Rat(25650) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • cow(519758) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Domestic Rabbit(100008749) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Horse(100033968) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • naked mole-rat(101701102) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • chicken(396529) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • dog(403966) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • domestic cat(101081858) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • sheep(443384) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • domestic guinea pig(100135483) ATPase, Na+/K+ transporting, beta 1 polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ATP1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, horse, human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, canine, human, mouse, pig, rat
Anwendung
ELISA
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Ouabain Octahydrat, ≥95% (HPLC), powder,
Spezies
rat, human
Digitoxin, ≥92% (HPLC), powder,
Spezies
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Digoxin, analytical standard,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Spezies

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Atp1b1,
Spezies
mouse
MISSION® esiRNA, targeting human ATP1B1,
Spezies
human