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ADSL

adenylosuccinate lyase

Synonyme:
AMPS, ASASE, ASL
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(158) Summary: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11564) adenylosuccinate lyase
  • Rat(315150) adenylosuccinate lyase
  • dog(474499) adenylosuccinate lyase
  • Zebrafish(334431) adenylosuccinate lyase
  • naked mole-rat(101719217) adenylosuccinate lyase
  • chicken(396540) adenylosuccinate lyase
  • cow(510949) adenylosuccinate lyase
  • domestic cat(101085644) adenylosuccinate lyase
  • sheep(101108120) adenylosuccinate lyase
  • domestic guinea pig(100713101) adenylosuccinate lyase

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ADSL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-ADSL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human ADSL,
Spezies
human
MISSION® esiRNA, targeting mouse Adsl,
Spezies
mouse