ABN14
Anti-Brain lipid binding protein Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Brain lipid-binding protein, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, brain lipid binding protein, fatty acid binding protein 7, brain, mammary-derived growth inhibitor-related
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All Photos(4)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse
species reactivity (predicted by homology)
human (based on 100% sequence homology)
packaging
antibody small pack of 25 μg
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Gene Information
human ... FABP7(2173)
mouse ... Fabp7(12140)
General description
BLBP (Brain lipid-binding protein) belongs to a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. BLBPs play essential roles in fatty acid uptake, transport and metabolism. BLBP can be used as a molecular marker for radial glia (a major neural progenitor cell type and a scaffolding supporting neuronal migration) in the developing central nervous system. Radial glia play an essential role in the generation of the cerebral cortex through their function as neuronal precursors and as neuronal migration guides.
Specificity
Rat homology - 88%.
This antibody recognizes Brain lipid-binding protein.
Immunogen
Epitope: Cytoplasmic Domain
GST-tagged recombinant protein corresponding to human Brain lipid-binding protein.
Application
Detect Brain lipid binding protein using this Anti-Brain lipid binding protein Antibody validated for use in WB, IH.
Immunohistochemistry Analysis: A 1:300 dilution of ABN14 antibody from a previous lot detected Brain lipid binding protein in mouse cerebellum tissue.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Quality
Evaluated by Western Blot in P1 mouse brain tissue lysate.
Western Blot Analysis: 0.01 µg/ml of this antibody detected Brain lipid-binding protein in 10 µg of P1 mouse brain tissue lysate.
Western Blot Analysis: 0.01 µg/ml of this antibody detected Brain lipid-binding protein in 10 µg of P1 mouse brain tissue lysate.
Target description
~ 15 kDa
Linkage
Replaces: AB9558
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
P1 mouse brain tissue lysate
P1 mouse brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Product No.
Description
Pricing
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Constance A Rich et al.
Glia, 66(12), 2617-2631 (2018-09-27)
We and others previously showed that in mouse embryos lacking the transcription factor Sox10, olfactory ensheathing cell (OEC) differentiation is disrupted, resulting in defective olfactory axon targeting and fewer gonadotropin-releasing hormone (GnRH) neurons entering the embryonic forebrain. The underlying mechanisms
Sara Anna Bonini et al.
Cerebral cortex (New York, N.Y. : 1991), 26(6), 2832-2849 (2016-03-08)
Alterations in genes that regulate neurodevelopment can lead to cortical malformations, resulting in malfunction during postnatal life. The NF-κB pathway has a key role during neurodevelopment by regulating the maintenance of the neural progenitor cell pool and inhibiting neuronal differentiation.
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells.
Malchenko, S; Sredni, ST; Hashimoto, H; Kasai, A; Nagayasu, K; Xie, J; Margaryan et al.
Testing null
Vivek K Bajpai et al.
Stem cells (Dayton, Ohio), 35(5), 1402-1415 (2017-02-01)
During development, neural crest (NC) cells are induced by signaling events at the neural plate border of all vertebrate embryos. Initially arising within the central nervous system, NC cells subsequently undergo an epithelial to mesenchymal transition to migrate into the
Shane Stegeman et al.
PloS one, 8(7), e68287-e68287 (2013-07-19)
The deubiquitylating enzyme Usp9x is highly expressed in the developing mouse brain, and increased Usp9x expression enhances the self-renewal of neural progenitors in vitro. USP9X is a candidate gene for human neurodevelopmental disorders, including lissencephaly, epilepsy and X-linked intellectual disability.
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