939625

Ethyl ethylene phospholane monomer

• Synonym(s): 2-Ethoxy-1,3,2-dioxaphospholane 2-oxide, Ethyl ethylene phophate
• Empirical Formula (Hill Notation): C₄H₉O₄P
• CAS Number: 823-31-4
• Molecular Weight: 152.09
• MDL number: MFCD28361141
• UNSPSC Code: 12162002

Properties

• form: liquid
• Quality Level: 100
• color: colorless
• storage temp.: −20°C
• SMILES string: O=P1(OCCO1)OCC
• InChI: 1S/C4H9O4P/c1-2-6-9(5)7-3-4-8-9/h2-4H2,1H3

Description

General description

Ethyl ethylene phospholane is a versatile monomer building block for the synthesis of biocompatible and biodegradable polymers. Ring opening polymerization (ROP) of this phospholane monomer in the presence of metal/organocatalysts yields poly(phosphoester)s (PPE) that are commonly used in biomedical research applications.

Application

Ethyl ethylene phospholane, also known as ethyl ethylene phophate or 2-ethoxy-1,3,2-dioxaphospholane 2-oxide, is used in many polymerization applications including:

• Polymer synthesis: This monomer is used as a building block to synthesize biodegradable and biocompatible polyphosphoesters

• Nanocarrier development: Polymers synthesized from the ehtyl ethylene phospholane monomer create efficient nanocarriers for drug delivery and gene therapy, including for use in targeted and controlled release of therapeutics

• Hydrogel fabrication: This monomer can be used to develop polymers for tissue engineering applications, offering scaffods with excellent biocompatibility and potential for cell growth and regeneration

Features and Benefits

Features and benefits of the ethyl ethylene phospholane include:

• Biocompatible and biodegradable: Through ring opening polymerization (ROP) of ethyl ethylene phospholane monomer, it is possible to synthesize polymers used in biomedical applications that are cell compatible and degrade over time

• Thermoresponsive behavior: In aqueous solutions, this monomer exhibits a lower critical solution temperature (LCST), making it responsive to changes in temperature, expanding its potential in controlled release system

• pH-responsive degradation: The resulting polymers can be designed to degrade at specific pH levels, allowing for targeted release of encapsulated substances

• Water soluble: This monomer enables the synthesis of water-soluble polymers, facilitating their incorporation into various aqueous formulations The biomedical research grade ethyl ethylene phospholane monomer opens the door to advanced biomaterials and provides researchers and developers with a powerful tool to create biocompatible and customizable polymers for a range of applications in biomedical research.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable