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SML1406

Sigma-Aldrich

Brassinazole

≥98% (HPLC), powder, brassinosteroid biosynthesis inhibitor

Synonyme(s) :

β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-1H-1,2,4-triazole-1-ethanol, (αR,βS)-rel-β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-1H-1,2,4-triazole-1-ethanol

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About This Item

Formule empirique (notation de Hill):
C18H18ClN3O
Numéro CAS:
280129-83-1
Poids moléculaire :
327.81
Code UNSPSC :
51111800
ID de substance PubChem :
329825853
Nomenclature NACRES :
NA.77

product name

Brassinazole, ≥98% (HPLC)

Niveau de qualité

100

Pureté

≥98% (HPLC)

Forme

powder

Couleur

white to beige

Solubilité

DMSO: 5 mg/mL, clear (warmed)

Température de stockage

2-8°C

Chaîne SMILES 

ClC1=CC=C(C[C@@H](N2N=CN=C2)[C@@](C)(O)C3=CC=CC=C3)C=C1

InChI

1S/C18H18ClN3O/c1-18(23,15-5-3-2-4-6-15)17(22-13-20-12-21-22)11-14-7-9-16(19)10-8-14/h2-10,12-13,17,23H,11H2,1H3/t17-,18+/m1/s1

Clé InChI

YULDTPKHZNKFEY-MSOLQXFVSA-N

Application

Brassinazole has been used in phenotype analyses to detect morphological changes in G-protein β subunit agb1 mutants.

Actions biochimiques/physiologiques

Brassinazole induces dwarfism and morphological changes in Arabidopsis, which results in similarity with brassinosteroid deficient mutants. These changes were neutralized by brassinolide treatment, indicating that brassinazole leads to brassinolide deficiency in Arabidopsis.
Brassinazole is an inhibitor of the biosynthesis of brassinosteroids, steroid hormones essential for plant growth and development. It has been used to study brassinosteroids function.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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T Asami et al.
Plant physiology, 123(1), 93-100 (2000-05-12)
Screening for brassinosteroid (BR) biosynthesis inhibitors was performed to find chemicals that induce dwarfism in Arabidopsis, mutants that resembled BR biosynthesis mutants that can be rescued by BR. Through this screening experiment, the compound brassinazole was selected as the most
Zhongtao Jia et al.
Plant physiology, 183(3), 998-1010 (2020-05-14)
Root developmental plasticity enables plants to adapt to limiting or fluctuating nutrient conditions in the soil. When grown under nitrogen (N) deficiency, plants develop a more exploratory root system by increasing primary and lateral root length. However, mechanisms underlying this
Arabidopsis G-Protein β Subunit AGB1 Interacts with BES1 to Regulate Brassinosteroid Signaling and Cell Elongation.
Zhang T, et al.
Frontiers in Plant Science, 8, 2225-2225 (2018)
Lijiang Hou et al.
Plant & cell physiology, 60(8), 1761-1777 (2019-05-18)
Brassinosteroid (BR) plays an important role in plant development and biotic and abiotic stress tolerance, but its specific function remains largely unknown in wheat (Triticum aestivum L.), preventing its utilization in this important crop. In this study, the function of
Xuejiao Cheng et al.
The Plant cell, 32(4), 923-934 (2020-02-16)
Six subspecies of hexaploid wheat (Triticumaestivum) have been identified, but the origin of Indian dwarf wheat (Triticum sphaerococcum), the only subspecies with round grains, is currently unknown. Here, we isolated the grain-shape gene Tasg-D1 in Tsphaerococcum via positional cloning. Tasg-D1
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