SAB4200394

Anti-Nestin (C-terminal) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody

• Synonyme(s) : Anti-NES
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~300 kDa
• Espèces réactives: mouse, rat
• Conditionnement: antibody small pack of 25 μL
• Validation améliorée: recombinant expression; Learn more about Antibody Enhanced Validation
• Concentration: ~1.5 mg/mL
• Technique(s): indirect immunofluorescence: 1-2 μg/mL using mouse P19 cells; western blot: 2-4 μg/mL using lysates of HEK293T cells over-expressing rat nestin.
• Numéro d'accès UniProt: P21263
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Nes(18008) ; rat ... Nes(25491)

Description

Description générale

Nestin/NES belongs to the intermediate filament (IF) protein family. Its expression is found in immature neuroepithelial and progenitor cell types. This 240 kDa protein contains the shortest head domain (N-terminus) and a long tail domain (C-terminus). Nestin is mapped to human chromosome 1q23.1.

Immunogène

synthetic peptide corresponding to a sequence at the C- terminus of mouse nestin, conjugated to KLH. The sequence is identical in rat nestin.

Application

Anti-Nestin (C-terminal) antibody has been used in immunostaining.

Actions biochimiques/physiologiques

Nestin/NES plays a major role in the modulation of assembly and disassembly of intermediate filaments, which in turn help in the remodeling of the cell along with other structural proteins.

Forme physique

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable