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K2753

Sigma-Aldrich

(±)-Ketamine hydrochloride

≥99% (HPLC), solid, NMDA glutamate receptor antagonist

Synonyme(s) :

(±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride

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About This Item

Formule empirique (notation de Hill):
C13H16ClNO · HCl
Numéro CAS:
1867-66-9
Poids moléculaire :
274.19
Numéro CE :
217-484-6
Numéro MDL:
MFCD00051420
Code UNSPSC :
12352116
ID de substance PubChem :
24896222
Nomenclature NACRES :
NA.77

product name

(±)-Ketamine hydrochloride, solid

Forme

solid

Contrôle du médicament

USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)

Température de stockage

2-8°C

Chaîne SMILES 

Cl.CNC1(CCCCC1=O)c2ccccc2Cl

InChI

1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H

Clé InChI

VCMGMSHEPQENPE-UHFFFAOYSA-N

Informations sur le gène

human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444)

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Actions biochimiques/physiologiques

Selective NMDA glutamate receptor antagonist; veterinary anesthetic.

Caractéristiques et avantages

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H336

Classification des risques

Acute Tox. 4 Oral - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificats d'analyse (COA)

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Songen Zhang et al.
Journal of leukocyte biology, 97(6), 1003-1010 (2015-01-15)
Streptococcus pyogenes of the M1 serotype can cause STSS, which is associated with significant morbidity and mortality. The purpose of the present study was to examine the role of NFAT signaling in M1 protein-induced lung injury. NFAT-luc mice were treated
Aude Castel et al.
BMC veterinary research, 9, 59-59 (2013-03-30)
Central post-stroke pain is a neuropathic pain condition caused by a vascular lesion, of either ischemic or hemorrhagic origin, in the central nervous system and more precisely involving the spinothalamocortical pathway responsible for the transmission of painful sensations. Few animal
R V Pustovit et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(5), 610-617 (2015-01-24)
Despite constipation being a common problem, the treatments that are available have side effects and are only partly effective. Recent studies show that centrally penetrant ghrelin receptor agonists cause defecation in humans and other species. Here, we describe some features
Hannes Hartman et al.
Digestive diseases and sciences, 60(5), 1284-1289 (2014-12-11)
The onset of acute pancreatitis (AP) is characterized by early protease activation followed by inflammation and organ damage, but the mechanisms are poorly understood. We hypothesized that histone deacetylase (HDAC) inhibition might exert protective effects on AP and investigated the
Scott A Schobel et al.
Neuron, 78(1), 81-93 (2013-04-16)
The hippocampus in schizophrenia is characterized by both hypermetabolism and reduced size. It remains unknown whether these abnormalities are mechanistically linked. Here we addressed this question by using MRI tools that can map hippocampal metabolism and structure in patients and
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Chromatograms

application for HPLC

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