OAW42

85073102, human ovary, Epithelial

• Synonyme(s) : OAW-42 Cells
• Code UNSPSC : 41106514

Propriétés

• product name: OAW42, 85073102
• Source biologique: human ovary
• Mode de croissance: Adherent
• Caryotype: 2n = 86
• Morphologie: Epithelial
• Produits: Not specified
• Récepteurs: Not specified
• Technique(s): cell culture | mammalian: suitable
• Maladie(s) pertinente(s): cancer
• Conditions d'expédition: dry ice
• Température de stockage: −196°C

Description

Origine de la lignée cellulaire

Human ovarian tumour epithelial

Description de la lignée cellulaire

From an ascites of patient with ovarian cystadenocarcinoma. Has retained ability to form free floating cysts in vitro and produces extracellular matrix. Has defined chemosensitivity pattern. Valuable for studies on biology of human ovarian cancer.

Application

OAW42 has been used to investigate the cytotoxic potential of histone deacetylase 1 as a target for ovarian cancer immunotherapy and to study the effects of tazemetostat, a potent and selective EZH2 inhibitor, on OAW42 cell lines.

Profil d'ADN

STR-PCR Data: Amelogenin: X
CSF1PO: 11
D13S317: 11
D16S539: 12,13
D5S818: 11,12
D7S820: 8
THO1: 6,7
TPOX: 8,11
vWA: 15,16

Milieu de culture

DMEM + 2mM Glutamine + 1mM Sodium Pyruvate (NaP) + 20 IU/l Bovine Insulin + 10% Foetal Bovine Serum (FBS).

Procédure de repiquage

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4x10,000 cells/cm² using 0.25% trypsin; 5% CO₂; 37°C.

Autres remarques

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