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675989

Sigma-Aldrich

Cyclopentyl methyl ether

greener alternative

contains 50 ppm BHT as inhibitor, ReagentPlus®, ≥99.90%

Synonyme(s) :

CPME

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About This Item

Formule empirique (notation de Hill):
C6H12O
Numéro CAS:
5614-37-9
Poids moléculaire :
100.16
Numéro MDL:
MFCD08276401
Code UNSPSC :
12352112
ID de substance PubChem :
329760630
Nomenclature NACRES :
NA.21

Niveau de qualité

100

Gamme de produits

ReagentPlus®

Pureté

≥99.90%

Forme

liquid

Contient

50 ppm BHT as inhibitor

Caractéristiques du produit alternatif plus écologique

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impuretés

≤50 ppm H2O2

Point d'ébullition

106 °C/760 mmHg

Pf

-140 °C

Densité

0.86 g/mL at 25 °C

Autre catégorie plus écologique

Aligned,

Chaîne SMILES 

COC1CCCC1

InChI

1S/C6H12O/c1-7-6-4-2-3-5-6/h6H,2-5H2,1H3

Clé InChI

SKTCDJAMAYNROS-UHFFFAOYSA-N

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Catégories apparentées

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Cyclopentyl methyl ether (CPME) is a greener alternative solvent to many aprotic ether solvents such as tetrahydrofuran (THF), 2-methyl tetrahydrofuran (2-MeTHF), dioxane (carcinogenic), tert-Butyl methyl ether (MTBE), and 1,2-dimethoxyethane (DME) and thus has been enhanced for "Safer Solvents and Auxiliaries".  Click here  for more information.

Application

CPME is a greener alternative solvent and may be used is a broad range of applications such as:

Organic synthesis reactions containing the following reagents and conditions:

  1. Alkali agents
  2. Lewis’s acid-mediated reactions
  3. Organometallic
  4. Reduction and Oxidation
  5. Transition metal catalysts
  6. Azeotropic water removal



Extraction of compounds
Polymer synthesis
Crystallization
Surface coatings

Caractéristiques et avantages

  • Synthetic-based sustainable and safer alternative
  • Reduces the number of steps required for production
  • Reduces the amount of water that is required for washing
  • Eliminates the need for co-solvents for product recovery

    It has many properties which make it a safer and greener alternative:
  • Low peroxide formation
  • High boiling point
  • Clean organic-water phase separation
  • Reduced energy to recover

Autres remarques

To see other BioRenewable or Greener Solvents

The toxicological assessment of cyclopentyl methyl ether (CPME) as a green solvent.




Informations légales

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameExclamation mark
GHS02,GHS07

Mention d'avertissement

Danger

Mentions de danger

H225,H302,H315,H319

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

<37.4 °F - closed cup

Point d'éclair (°C)

< 3 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Replacement of dichloromethane within chromatographic purification: a guide to alternative solvents
MacMillan, D.S.; et al.
Green Chemistry (2012)
Cyclopentyl Methyl Ether as a New and Alternative Process Solvent
Watanabe, K.; Yamagiwa, N.; Torisawa, Y.
Organic Process Research & Development, 11 (2007)
Rikako Takahiro et al.
Biological & pharmaceutical bulletin, 38(1), 58-65 (2015-03-07)
The aim of this study was to characterize the kinetics of metabolite formation of the phosphodiesterase type-5 (PDE5) inhibitors sildenafil and tadalafil by CYP3A4, CYP3A5, and CYP3A7 isoforms. The formations of N-desmethyl sildenafil and desmethylene tadalafil were examined using CYP3A

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Biorenewable Solvents

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