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P0250000

Pancuronium bromide

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(Acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide

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About This Item

Formule empirique (notation de Hill):
C35H60Br2N2O4
Numéro CAS:
15500-66-0
Poids moléculaire :
732.67
Numéro Beilstein :
4226892
Numéro MDL:
MFCD00079223
Code UNSPSC :
41116107
ID de substance PubChem :
329820026
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

pancuronium 

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

[Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](OC(C)=O)[C@H](C[C@@]34[H])[N+]5(C)CCCCC5)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]6(C)CCCCC6

InChI

1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1

Clé InChI

NPIJXCQZLFKBMV-YTGGZNJNSA-L

Informations sur le gène

human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pancuronium bromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301

Conseils de prudence

P301 + P330 + P331 + P310

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Consulter la Bibliothèque de documents

Alina Teliban et al.
Journal of neurophysiology, 111(10), 2071-2083 (2014-02-28)
Intact and injured cutaneous C-fibers in the rat sural nerve are cold sensitive, heat sensitive, and/or mechanosensitive. Cold-sensitive fibers are either low-threshold type 1 cold sensitive or high-threshold type 2 cold sensitive. The hypothesis was tested, in intact and injured
J Simoes et al.
Journal of perinatology : official journal of the California Perinatal Association, 9(2), 215-218 (1989-06-01)
Nursing care of the newborn in respiratory distress has become highly sophisticated and technical, requiring skill in principles of neonatal assessment and therapeutic interventions. It is important to be knowledgeable about the technical aspects of the equipment and monitors. However
Pancuronium bromide: a review of its pharmacological properties and clinical application.
T M Speight et al.
Drugs, 4(3), 163-226 (1972-01-01)
M F Roizen et al.
Annals of internal medicine, 88(1), 64-68 (1978-01-01)
Pancuronium bromide is a nondepolarizing muscle relaxant approved to induce skeletal muscle relaxation during anesthesia and to facilitate the management of patients undergoing mechanical ventilation. The use of pancuronium bromide during surgery led to the appreciation that it has advantages
M Bączyk et al.
The Journal of physiology, 592(19), 4313-4328 (2014-08-03)
The main aim of the present study was to examine to what extent long-lasting subcortical actions of transcranial direct current stimulation (tDCS) may be related to its presynaptic actions. This was investigated in the red nucleus, where tDCS was recently
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