E9884

Ethylenediaminetetraacetic acid

ACS reagent, 99.4-100.6%, powder

• Synonyme(s) : (Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
• Formule linéaire : (HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂
• Numéro CAS: 60-00-4
• Poids moléculaire : 292.24
• Numéro Beilstein : 1716295
• Numéro CE : 200-449-4
• Numéro MDL: MFCD00003541
• Code UNSPSC : 12352106
• eCl@ss : 39030907
• ID de substance PubChem : 24894705
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 200
• Qualité: ACS reagent
• Agence: suitable for SM 4500 - NH3
• Pureté: 99.4-100.6%
• Forme: powder
• Pertinence de la réaction: reagent type: chelator
• Impuretés: ≤0.005% insoluble matter; ≤0.1% Nitrilotriacetic acid ([HOCOCH₂]₃N)
• Résidus de calcination: ≤0.2%
• pH: 2.5 (23 °C, 10 g/L)
• Pf: 250 °C (dec.) (lit.)
• Solubilité: water: soluble 0.4 g/L at 20 °C
• Traces de cations: Ca: ≤0.001%; Fe: ≤0.005%; Mg: ≤5 ppm; heavy metals: ≤0.001% (byICP-OES)
• Chaîne SMILES: OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
• InChI: 1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
• Clé InChI: KCXVZYZYPLLWCC-UHFFFAOYSA-N

Description

Description générale

Ethylenediaminetetraacetic acid (EDTA) is a hydrophilic metal chelating agent that transforms metal ions into inactive, cyclic metal complexes. Hence, it has industrial application for resolving metal contamination.

Application

Ethylenediaminetetraacetic acid has been used:

• as a component of labeling buffer, which is used in the washing step during cell fractionation{155)
• for investigating the effect of papain enzyme on wound debridement and other skin issues
• for harvesting rat arterial smooth muscle cell after its pre-treatment for its use in flow cytometry analysis

Actions biochimiques/physiologiques

Ethylenediaminetetraacetic acid (EDTA) is not easily administered by the gastrointestinal tract. Intravenous administration of sodium EDTA results in hypocalcemic tetany. It is generally useful in plasma or molecular diagnostics and acts by chelating calcium. EDTA serves as an anticoagulant for haematological cell counting and cell morphological analysis.

Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H319
• Conseils de prudence: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves