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Key Documents

MAB5674

Sigma-Aldrich

Anti-Plectin Antibody, Clone 10F6

clone 10F6, Chemicon®, from mouse

Synonyme(s) :

Plackin

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

10F6, monoclonal

Espèces réactives

mouse, human, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès UniProt

P30427

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ACTC1(70) , ACTG1(71)

Description générale

The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other tissues. It also may regulate changes of lymphocyte cytoarchitecture during polarization and extravasation. This gene has alternative splicing of different 5′ exons to the first constant exon, which generates transcript variants that encode distinct isoforms

Spécificité

Cat. # MAB5674 recognizes the cytoplasmic domain of Plectin.
Reactivity with other species has not been tested.

Immunogène

Gel-purified C5 Cell plectin

Application

Detect Plectin using this Anti-Plectin Antibody, Clone 10F6 validated for use in WB, IH.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Neuronal & Glial Markers

Qualité

Routinely tested on rat brain tissue lysate

Description de la cible

300-500 kDa

Forme physique

Format: Purified
Purified in PBS with 0.05% NaN3

Stockage et stabilité

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Remarque sur l'analyse

Control
rat brain tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Elena Ambrosini et al.
Glia, 41(3), 290-300 (2003-01-16)
Macrophage inflammatory protein-3alpha/CCL20 is a recently identified chemokine that binds to CCR6 and acts as a chemoattractant for memory/differentiated T-cells, B-cells, and immature dendritic cells. We have previously reported that CCL20 and CCR6 mRNAs are expressed in the CNS of
Sarah D Ackerman et al.
The Journal of experimental medicine, 215(3), 941-961 (2018-01-26)
Myelin is a multilamellar sheath generated by specialized glia called Schwann cells (SCs) in the peripheral nervous system (PNS), which serves to protect and insulate axons for rapid neuronal signaling. In zebrafish and rodent models, we identify GPR56/ADGRG1 as a

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