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Key Documents

AB15452

Sigma-Aldrich

Anti-MAP2 Antibody

Chemicon®, from chicken

Synonyme(s) :

Microtubule associated protein 2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

chicken

Niveau de qualité

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Map2(17756)

Spécificité

MAP2 [Microtubule associated protein 2]
Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.

Immunogène

Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.

Application

Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Forme physique

Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
ImmunoAffinity Purified

Stockage et stabilité

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Yun Yang et al.
Nature communications, 13(1), 159-159 (2022-01-12)
Abnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer's disease (AD), but their relationship to disease pathogenesis and to each other remains unclear. Here we show that succinylation, a
Andrew R Snavely et al.
Disease models & mechanisms, 15(12) (2022-11-19)
The proteosome inhibitor bortezomib has revolutionized the treatment of multiple hematologic malignancies, but in many cases, its efficacy is limited by a dose-dependent peripheral neuropathy. We show that human induced pluripotent stem cell (hiPSC)-derived motor neurons and sensory neurons provide
Hae-Jin Kweon et al.
Cell reports, 32(6), 108025-108025 (2020-08-14)
The α7 nicotinic acetylcholine receptor participates in diverse aspects of brain physiology and disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic reticulum (ER)-localized integral membrane protein. By constructing α7 chimeras and mutants, we find that NACHO
Sarra Djemil et al.
Journal of neurochemistry, 153(4), 468-484 (2019-12-11)
Nicotinic acetylcholine receptors (nAChRs) are known to play a role in cognitive functions of the hippocampus, such as memory consolidation. Given that they conduct Ca2+ and are capable of regulating the release of glutamate and γ-aminobutyric acid (GABA) within the
Swati Agarwal et al.
Anesthesiology, 137(2), 212-231 (2022-05-04)
Inhalational anesthetics are known to disrupt PDZ2 domain-mediated protein-protein interactions of the postsynaptic density (PSD)-95 protein. The aim of this study is to investigate the underlying mechanisms in response to early isoflurane exposure on synaptic PSD-95 PDZ2 domain disruption that

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