528215

Anti-PAI-1 Mouse mAb (MA-33B8)

liquid, ≥90% (SDS-PAGE), clone MA-33B8

• Synonyme(s) : Anti-Plasminogen Activator Inihibitor-1
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified antibody
• Type de produit anticorps: primary antibodies
• Clone: MA-33B8, monoclonal
• Pureté: ≥90% (SDS-PAGE)
• Forme: liquid
• Ne contient pas: preservative
• Espèces réactives: rabbit, human
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; avoid repeated freeze/thaw cycles
• Isotype: IgG
• Conditions d'expédition: wet ice
• Température de stockage: −70°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... SERPINE1(5054)

Description

Description générale

Purified mouse monoclonal antibody. Recognizes the ~50 kDa PAI-1 protein.

Recognizes the ~50 kDa PAI-1 protein.

This Anti-PAI-1 Mouse mAb (MA-33B8) is validated for use in Immunoblotting, Neutralization Studies for the detection of PAI-1.

Immunogène

Human

human tPA-PAI-1 complex

Application

Immunoblotting (10 µg/ml)

Neutralization Studies (see application references)

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Autres remarques

Montes, R., et al. 2000. Thromb. Haemost.84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem.274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta1337, 257.

Rapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable